SEEK ID: https://armlifebank.am/people/2
Location:
Armenia
ORCID:
https://orcid.org/0000-0002-6851-1056
Joined: 16th Feb 2024
Expertise: Not specified
Tools: Not specified
Roles
Admin
Project administrator
- Sex-specific differences in long-term gamma and simGCRsim-associated alterations in deferential gene expression in the heart tissue
- Functional Genomics of Vine
- Molecular Profiling of Cancer Metastases
- Omics-Based Insights into Human Long-Term Exposure to Environmental Metals
- Biological pathway activity analysis
- ML approaches for omic data analysis
- Tools for Telomere Biology
- Molecular characterization of cancers with long-read RNA sequencing
- Low dose radiation risks: present research and future perspectives
- Third International Congress "CRISPR-2025"
- International Summit in Immuno-Oncology
Programme administrator
Their tagsRelated items
- Programmes (8)
- Projects (14)
- Institutions (2)
- Investigations (1)
- Data files (6)
- Models (2)
- Publications (73)
- Presentations (11)
- Events (2)
- Documents (4)
- Sample types (1)
- Samples (4)
- Collections (1)
The Armenian Genome Project aims at unraveling our genetic background and bringing personalized and precision medicine to Armenia
Projects: Genetic History of Armenians
Web page: http://armeniangenome.am/
This Programme sumarizes scientific events and associated documents.
Projects: Low dose radiation risks: present research and future perspectives, Third International Congress "CRISPR-2025", International Summit in Immuno-Oncology
Web page: Not specified
The Plant Genomics Programme focuses on the comprehensive characterization of plant genetic resources, aiming to understand the factors that shape genetic variation across plant genomes and drive phenotypic diversity in traits of adaptive and economic importance. The research explores the genetic architecture of plant adaptation to changing climatic conditions and investigates the genomic determinants of genetic diversity. A key objective is the integration of multi-omics data into innovative ...
Projects: Functional Genomics of Vine, Armenian Wine Genome Program
Web page: Not specified
This Programme focuses on the development, implementation, and application of bioinformatics tools for the analysis of large-scale genomic datasets. It aims to facilitate the processing, integration, and interpretation of high-throughput sequencing data, including whole-genome, transcriptome, and epigenome analyses. The Programme encompasses computational approaches for variant discovery, gene expression profiling, network biology, and multi-omics data integration.
Projects: Biological pathway activity analysis, ML approaches for omic data analysis, Tools for Telomere Biology
Web page: Not specified
Cellular dysfunction, the fundamental basis of all human diseases, underpins the pathophysiology of numerous disorders. This program presents a overview of research initiatives focused on advancing human health through the development of diagnostic, preventive, and therapeutic strategies. These projects are conducted in collaboration with multiple research institutions and are supported by diverse grant funding mechanisms.
Projects: Study of the molecular mechanisms of familial Mediterranean fever using genetic engineering and functional genomics, Development of induced pluripotent stem cell bank of patients with Familial Mediterranean Fever
Web page: Not specified
The “Low dose radiation risks: present research and future perspectives” Advanced Research Workshop is a NATO (North Atlantic Treaty Organization)-sponsored workshop organized by the McMaster University (Canada) and Institute of Molecular Biology NAS RA (National Academy of Sciences of Republic of Armenia) which offers a unique opportunity to learn about new discoveries and exchange experience with professionals in the field of radioecology, radiobiology, country-specific regulatory agencies, ...
Programme: Events
Public web page: https://imb.am/rad2025/
Start date: 30th Mar 2025
End date: 2nd Apr 2025
Organisms: Not specified
We are pleased to invite your specialists to the International Summit in Immuno-Oncology, which will take place in Yerevan, Armenia, on October 16–18, 2025, organized by Santé Arménie in collaboration with Inserm, the Armenian Association of Clinical Pathologists and Cytologists, and the Institute of Molecular Biology.
This summit marks the beginning of an ambitious effort to establish a world-class immuno-oncology ecosystem in Armenia. We are gathering leading experts in cancer research, clinical ...
Organisms: Not specified
We are delighted to announce the Third International Congress “CRISPR-2025,” which will take place from October 5–10, 2025, in Yerevan, Armenia.
CRISPR-2025 will provide a dynamic platform for experts to discuss cutting-edge advancements, ongoing challenges, and ethical considerations in genome editing technologies. The congress will foster collaboration and the exchange of ideas among scientists, clinicians, and industry leaders, creating opportunities for innovative partnerships.
The topics to ...
Programme: Events
Public web page: https://crispr2025.rau.am/
Start date: 5th Oct 2025
End date: 10th Oct 2025
Organisms: Not specified
Principal Investigator: Prof. Hans Binder
University: University of Leipzig
Research Group: Kristina Margaryan, Maria Nikoghosyan, Tomas Konecny, Anush Baloyan, Hripsime Gasoyan, Emma Hovhannisyan, Levon Galstyan, Duan Shengchang
Duration: 2023-2027
Co-implementing and hosting partner: Armenian Bioinformatics Institute (ABI) and Institute of Molecular Biology
Project Importance The cultivated grape (Vitis vinifera) has become the world’s leading fruit crop. Grape is unique not only because it is ...
Programme: Plant Genomics & Bioinformatics
Public web page: https://www.fast.foundation/en/program/847/2022/new_tab/6586/6677
Organisms: Grapevine
Programme: Plant Genomics & Bioinformatics
Public web page: Not specified
Organisms: Grapevine
DigitalLife aims at bringing together complementary Armenian and German competence of the project partners in three major areas: omics bioinformatics for health with single-cell omics resolution, the establishment of infrastructure for genomic data collection, analysis, and sharing, and the Research School offering a qualification program for young scientists. The research tasks include the development of pathway analysis and machine learning methods and software for single-cell omic data analysis, ...
Snapshots: No snapshots
The dataset contains raw and intermediated files, and scripts required to reproduce the results associated with the manuscript "Assigning transcriptomic subtypes to CLL samples using nanopore RNA-sequencing and self-organizing maps". Here, we demonstrate that integrating publicly available short-read data with in-house generated ONT data, along with the application of machine learning approaches, enables the characterization of the CLL transcriptome landscape, the identification of clinically ...
Creator: Arsen Arakelyan
Submitter: Lana Karapetyan
Investigations: No Investigations
Studies: No Studies
Assays: No Assays
This is a supplementary dataset with raw data, scripts, and complete analysis results for the paper "Supervised projection of high-dimensional genome-wide expression on SOM transcriptome landscapes".
The archive contains three folders:
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"Simdata" folder contains data, scripts, and results of performance evaluation of extension SOM and supervised SOM with simulated data.
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"IBD" - folder contains data, scripts, and results of analysis of Inflammatory bowel disease datasets.
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"BC" - folder ...
Creators: Maria Nikoghosyan, Suren Davitavyan, Hans Binder, Arsen Arakelyan
Submitter: Lana Karapetyan
Investigations: No Investigations
Studies: No Studies
Assays: No Assays
This is the submission accompanying the "Telomere Maintenance Pathways in Lower-Grade Gliomas: Insights from Genetic Subtypes and Telomere Length Dynamics" paper.
The dataset contains the TCGA and CGGA LGG
The dataset is organized as follows:
Folder "CGGA_LGG_IDH_subtype_mean_vis" - The CGGAL GG data IDH subtype pathway visualization and CSV data. Folder "Long_Short_telomeres_path_vis" - The TCGA LGG data ALT and TEL pathway visualization for Long and Short telomeres mean values. Folder ...
Creators: Arsen Arakelyan, Meline Hakobyan, Hans Binder
Submitter: Arsen Arakelyan
Investigations: No Investigations
Studies: No Studies
Assays: No Assays
Sequencing raw data.
Creators: Arsen Arakelyan, Siras Hakobyan
Submitter: Arsen Arakelyan
Investigations: No Investigations
Studies: No Studies
Assays: No Assays
This dataset provides data necessary to replicate the results of the time-perturbation analysis of gene expression in health and mental disorders. The corresponding code is available in the GitHub repository under the https://github.com/susieavagyan/BrainExp-TemporalDynamics link.
Creator: Arsen Arakelyan
Submitter: Arsen Arakelyan
Investigations: No Investigations
Studies: No Studies
Assays: No Assays
The Pathway Signal Flow (PSF) toolkit is an R package designed for pathway editing and signal flow analysis. It enables users to perform PSF analysis on functional -omics data, facilitating the study of signaling pathways in various biological contexts.
Key Features:
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Pathway Editing: Allows customization and editing of biological pathways to suit specific research needs.
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Signal Flow Calculation: Computes signal flow within pathways based on gene expression data, aiding in the ...
Creators: Arsen Arakelyan, Siras Hakobyan
Submitter: Arsen Arakelyan
Model type: Not specified
Model format: Not specified
Environment: Not specified
Organism: Not specified
Investigations: No Investigations
Studies: No Studies
Assays: No Assays
KEGG pathway database is a collection of manually drawn pathway maps representing current knowledge on molecular interaction and reaction networks, accompanied with KGML (KEGG pathway xml format) files for automatic computational analyses and modeling of metabolic and signaling networks. In a KGML file the pathway is represented as a graph object with entry elements (gene products, compounds, pathways) as its nodes, and relations between elements as edges. However, in most cases there is a lack ...
Creator: Arsen Arakelyan
Submitter: Arsen Arakelyan
Model type: Not specified
Model format: Not specified
Environment: Matlab
Organism: Not specified
Investigations: No Investigations
Studies: No Studies
Assays: No Assays
Abstract (Expand)
Authors: Siras Hakobyan, Maria Schmidt, H. Binder, A. Arakelyan
Date Published: 14th Aug 2025
Publication Type: Journal
DOI: 10.7717/peerj.19729
Citation:
Abstract (Expand)
Authors: Roksana Zakharyan, Siras Hakobyan, Agnieszka Brojakowska, Malik Bisserier, Shihong Zhang, Mary K. Khlgatian, Amit Kumar Rai, Suren Davitavyan, Ani Stepanyan, Tamara Sirunyan, Gisane Khachatryan, Susmita Sahoo, Venkata Naga Srikanth Garikipati, Arsen Arakelyan, David A. Goukassian
Date Published: 21st Jul 2025
Publication Type: Journal
DOI: 10.1038/s41526-025-00506-8
Citation: npj Microgravity,11(1)
Abstract (Expand)
Authors: Meline Hakobyan, Hans Binder, Arsen Arakelyan
Date Published: 28th Apr 2025
Publication Type: Journal
DOI: 10.3390/ijms26094175
Citation: International Journal of Molecular Sciences,26(9):4175
Abstract (Expand)
Authors: A. Stepanyan, A. Arakelyan, J. Schug
Date Published: 24th Mar 2025
Publication Type: Journal
PubMed ID: 40023890
Citation: Environ Int. 2025 Mar;197:109344. doi: 10.1016/j.envint.2025.109344. Epub 2025 Feb 21.
Abstract (Expand)
Authors: A. Arakelyan, T. Sirunyan, G. Khachatryan, S. Hakobyan, A. Minasyan, M. Nikoghosyan, M. Hakobyan, A. Chavushyan, G. Martirosyan, Y. Hakobyan, H. Binder
Date Published: 13th Mar 2025
Publication Type: Journal
PubMed ID: 40149301
Citation: Cancers (Basel). 2025 Mar 13;17(6):964. doi: 10.3390/cancers17060964.
Start Date: 5th Oct 2025 (5th Oct 2025 (Asia/Yerevan))
End Date: 10th Oct 2025 (10th Oct 2025 (Asia/Yerevan))
Event Website: https://crispr2025.rau.am/
Country:
Armenia
City: Yerevan
The “Low dose radiation risks: present research and future perspectives” Advanced Research Workshop is a NATO (North Atlantic Treaty Organization)-sponsored workshop organized by the McMaster University (Canada) and Institute of Molecular Biology NAS RA (National Academy of Sciences of Republic of Armenia) which offers a unique opportunity to learn about new discoveries and exchange experience with professionals in the field of radioecology, radiobiology, country-specific regulatory agencies, ...
Start Date: 29th Mar 2025 (30th Mar 2025 (Asia/Yerevan))
End Date: 1st May 2025 (2nd May 2025 (Asia/Yerevan))
Event Website: https://imb.am/rad2025/
Country:
Armenia
City: Yerevan
16-18 OCTOBER 2025 YEREVAN, ARMENIA
AGENDA
Creators: Lana Karapetyan, Arsen Arakelyan
Submitter: Lana Karapetyan
Investigations: No Investigations
Studies: No Studies
Assays: No Assays
- Cell Technologies
- Regenerative Medicine
- Intelligent Data Science
- Synthetic Biology
- Postgenome
- Research & Development
OCTOBER 5-10, 2025 YEREVAN, ARMENIA
Creators: Lana Karapetyan, Arsen Arakelyan
Submitter: Lana Karapetyan
Investigations: No Investigations
Studies: No Studies
Assays: No Assays
Creator: Arsen Arakelyan
Submitter: Arsen Arakelyan
Investigations: No Investigations
Studies: No Studies
Assays: No Assays
Creator: Arsen Arakelyan
Submitter: Arsen Arakelyan
Investigations: No Investigations
Studies: No Studies
Assays: No Assays
Patient-specific induced pluripotent stem cells (iPSCs) are reprogrammed somatic cells derived from individual patients through the expression of key transcription factors (e.g., OCT4, SOX2, KLF4, and c-MYC). These cells exhibit pluripotency, allowing them to differentiate into various cell types and serve as in vitro models for studying disease mechanisms, drug screening, and regenerative medicine.
Sample Name (String) *, Type (String) *, Condition (String) *, Link (String) , Location (String)
Not specified
Type: Patient-specific induced pluripotent stem cells (iPSCs)
Creators: Arsen Arakelyan, Lana Karapetyan, Roksana Zakharyan
Submitter: Arsen Arakelyan
Type: Patient-specific induced pluripotent stem cells (iPSCs)
Creators: Arsen Arakelyan, Lana Karapetyan, Roksana Zakharyan
Submitter: Arsen Arakelyan
Type: Patient-specific induced pluripotent stem cells (iPSCs)
Creators: Arsen Arakelyan, Lana Karapetyan, Roksana Zakharyan
Submitter: Arsen Arakelyan
Type: Patient-specific induced pluripotent stem cells (iPSCs)
Creators: Arsen Arakelyan, Lana Karapetyan, Roksana Zakharyan
Submitter: Arsen Arakelyan
Archive contains presentation slides and recorded talks of the “Low dose radiation risks: present research and future perspectives” Advanced Research Workshop.
External Link
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