Deciphering the Fine-Scaled Temporal Changes in Microbiome Communities Following Antibiotic Exposure

We develop bioinformatics algorithms and tools to explore the temporal dynamics of microbiome communities in response to environmental perturbations and treatments. We seek to understand the mechanisms through which the direct effects of perturbations propagate via microbial interaction networks, leading to changes in microbiome composition over time.Through application of these techniques we study antibiotic resistance in complex microbial communities, the impact of pesticides on bee gut microbiome and host-microbiome interactions in inflammatory bowel disease.