SEEK ID: https://armlifebank.am/people/24
Location:
Armenia
ORCID:
https://orcid.org/0000-0001-8525-420X
Joined: 2nd Apr 2025
Expertise: Not specified
Tools: Not specified

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This program is designed to encapsulate and facilitate research projects focusing on the intricate dynamics between genetic predispositions and environmental factors in the progression of chronic diseases, excluding cancer. This initiative aims to unravel the molecular mechanisms and pathways that underlie these diseases, thereby paving the way for targeted interventions and therapies.
Projects: Mental disorders and aging brain, Omics-Based Insights into Human Long-Term Exposure to Environmental Metals, Deciphering the Fine-Scaled Temporal Changes in Microbiome Communities Following Antibiotic Exposure, Telomere-related biomarkers of disease in liquid biopsies
Web page: Not specified
We investigate telomeric fragments in cell-free DNA in blood plasma in disease. We aim to develop novel diagnostic approaches to identify and monitor disease status in cancers and chronic disorders through liquid biopsies.
Programme: Genes, Environment and Chronic Diseases
Public web page: Not specified
Organisms: Human
We develop bioinformatics algorithms and tools to explore the temporal dynamics of microbiome communities in response to environmental perturbations and treatments. We seek to understand the mechanisms through which the direct effects of perturbations propagate via microbial interaction networks, leading to changes in microbiome composition over time.Through application of these techniques we study antibiotic resistance in complex microbial communities, the impact of pesticides on bee gut microbiome ...
Programme: Genes, Environment and Chronic Diseases
Public web page: Not specified
Organisms: Human, Microbiome
Abstract (Expand)
Authors: S. Huch, L. Nersisyan, M. Ropat, D. Barrett, M. Wu, J. Wang, V. D. Valeriano, N. Vardazaryan, J. Huerta-Cepas, W. Wei, J. Du, L. M. Steinmetz, L. Engstrand, V. Pelechano
Date Published: 5th Jun 2023
Publication Type: Journal
PubMed ID: 37217719
Citation: Nat Microbiol. 2023 Jun;8(6):1123-1136. doi: 10.1038/s41564-023-01393-z. Epub 2023 May 22.