Programmes

What is a Programme?
10 Programmes found

This programme aims to implement genomic epidemiology approaches to characterize the genetic determinants of antimicrobial resistance, identify transmission pathways, and monitor the dissemination of high-risk bacterial clones across healthcare settings in Armenia. Using whole-genome sequencing (WGS), bioinformatics analyses, and integration of epidemiological data, the project will investigate the priority drug-resistant pathogens associated with the spread of difficult-to-treat infections in ...

Projects: Molecular epidemiology of multi-drug resistance

Web page: Not specified

Principal Investigator: Prof. David Goukassian

University: Icahn School of Medicine at Mount Sinai

Duration:2023-2027

Hosting partner: Institute of Molecular Biology NAS RA (IMB)

Project Importance The high likelihood of developing genomic instability due to exposure to ionizing radiation suggests that exposure can cause DNA damage to hematopoietic stem cells (HSCs), promoting the development of somatic mutations that can lead to aberrant clonal events. Thus, it is conceivable that space ...

Projects: Sex-specific differences in long-term gamma and simGCRsim-associated alterations in differential gene expression in the heart tissue

Web page: https://fast.foundation/en/program/847/2022/new_tab/6586/7014

This program is dedicated to the discovery and study of new antiviral drugs against human and animal viruses, including influenza A and B, herpes simplex virus type 1, and African swine fever virus. Computational methods and in vitro assays are combined to identify new antiviral agents. The mechanism of action of the most promising compounds is studied using various cellular approaches.

Projects: Discovery of new antiviral compounds by combining in silico and in vitro methods, MAPK/ERK pathway inhibitors as novel antiviral compounds, African swine fever virus

Web page: Not specified

The Armenian Genome Project aims at unraveling our genetic background and bringing personalized and precision medicine to Armenia

Projects: Genetic History of Armenians, Whole genome and whole exome sequencing based analysis of diversity of genomic variants in Armenian population

Web page: http://armeniangenome.am/

The Plant Genomics Programme focuses on the comprehensive characterization of plant genetic resources, aiming to understand the factors that shape genetic variation across plant genomes and drive phenotypic diversity in traits of adaptive and economic importance. The research explores the genetic architecture of plant adaptation to changing climatic conditions and investigates the genomic determinants of genetic diversity. A key objective is the integration of multi-omics data into innovative ...

Projects: Functional Genomics of Vine, Armenian Wine Genome Program

Web page: Not specified

This Programme focuses on the development, implementation, and application of bioinformatics tools for the analysis of large-scale genomic datasets. It aims to facilitate the processing, integration, and interpretation of high-throughput sequencing data, including whole-genome, transcriptome, and epigenome analyses. The Programme encompasses computational approaches for variant discovery, gene expression profiling, network biology, and multi-omics data integration.

Projects: Biological pathway activity analysis, ML approaches for omic data analysis, Tools for Telomere Biology

Web page: Not specified

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