Genes, Environment and Chronic Diseases
This program is designed to encapsulate and facilitate research projects focusing on the intricate dynamics between genetic predispositions and environmental factors in the progression of chronic diseases, excluding cancer. This initiative aims to unravel the molecular mechanisms and pathways that underlie these diseases, thereby paving the way for targeted interventions and therapies.
Web page: Not specified
Funding details: Related items
Projects: Sex-specific differences in long-term gamma and simGCRsim-associated alterations in deferential gene expression in the heart tissue, Functional Genomics of Vine, Molecular Profiling of Cancer Metastases, Study of the molecular mechanisms of familial Mediterranean fever using genetic engineering and functional genomics, Mental disorders and aging brain, Omics-Based Insights into Human Long-Term Exposure to Environmental Metals, Biological pathway activity analysis, ML approaches for omic data analysis, Tools for Telomere Biology, Armenian Wine Genome Program, Molecular characterization of cancers with long-read RNA sequencing, Low dose radiation risks: present research and future perspectives
Institutions: Institute of Molecular Biology NAS RA, Armenian Bioinformatics Institute
https://orcid.org/0000-0002-6851-1056
Projects: Functional Genomics of Vine, Molecular Profiling of Cancer Metastases, Biological pathway activity analysis, Mental disorders and aging brain, ML approaches for omic data analysis
Institutions: Armenian Bioinformatics Institute, Interdisciplinary Center for Bioinformatics (IZBI)
https://orcid.org/0000-0002-2242-4678
Projects: Mental disorders and aging brain
Institutions: Institute of Molecular Biology NAS RA
Long-term environmental exposure to metals leads to epigenetic changes and may increase risks to human health. The human epidemiologic and the toxicologic animal model studies provide strong evidence of metal exposure related DNA methylation changes, and, consequently alterations in gene expression, in metabolic, genetic and signal transduction pathways and their functions. The current study is designed to investigate genome wide DNA methylation and transcriptomic changes induced by human chronic ...
Programme: Genes, Environment and Chronic Diseases
Public web page: Not specified
Start date: 1st Feb 2020
This project focuses on studies around brain disorders and ageing.
Programme: Genes, Environment and Chronic Diseases
Public web page: Not specified
This dataset provides data necessary to replicate the results of the time-perturbation analysis of gene expression in health and mental disorders. The corresponding code is available in the GitHub repository under the https://github.com/susieavagyan/BrainExp-TemporalDynamics link.
Creator: Arsen Arakelyan
Submitter: Arsen Arakelyan
External Link
This dataset provides data necessary to replicate the results of the time-perturbation analysis of gene expression in health and mental disorders. The corresponding code is available in the GitHub repository under the https://github.com/susieavagyan/BrainExp-TemporalDynamics link.
Creator: Arsen Arakelyan
Submitter: Arsen Arakelyan
Abstract (Expand)
Authors: A. Stepanyan, A. Arakelyan, J. Schug
Date Published: 24th Mar 2025
Publication Type: Journal
Abstract (Expand)
Authors: A. Arakelyan, S. Avagyan, A. Kurnosov, T. Mkrtchyan, G. Mkrtchyan, R. Zakharyan, K. R. Mayilyan, H. Binder
Date Published: 17th Feb 2024
Publication Type: Journal
Abstract (Expand)
Authors: A. Stepanyan, A. Petrackova, S. Hakobyan, J. Savara, S. Davitavyan, E. Kriegova, A. Arakelyan
Date Published: 7th Aug 2023
Publication Type: Journal
Abstract (Expand)
Authors: H. Loeffler-Wirth, L. Hopp, M. Schmidt, R. Zakharyan, A. Arakelyan, H. Binder
Date Published: 21st Jan 2022
Publication Type: Journal
