This program is designed to encapsulate and facilitate research projects focusing on the intricate dynamics between genetic predispositions and environmental factors in the progression of chronic diseases, excluding cancer. This initiative aims to unravel the molecular mechanisms and pathways that underlie these diseases, thereby paving the way for targeted interventions and therapies.
Web page: Not specified
Funding details:Related items
Projects: Sex-specific differences in long-term gamma and simGCRsim-associated alterations in deferential gene expression in the heart tissue, Functional Genomics of Vine, Molecular Profiling of Cancer Metastases, Omics-Based Insights into Human Long-Term Exposure to Environmental Metals, Biological pathway activity analysis, ML approaches for omic data analysis, Tools for Telomere Biology, Mental disorders and aging brain, Armenian Wine Genome Program, Study of the molecular mechanisms of familial Mediterranean fever using genetic engineering and functional genomics, Molecular characterization of cancers with long-read RNA sequencing, Low dose radiation risks: present research and future perspectives
Institutions: Institute of Molecular Biology NAS RA, Armenian Bioinformatics Institute

Projects: Functional Genomics of Vine, Molecular Profiling of Cancer Metastases, Biological pathway activity analysis, Mental disorders and aging brain, ML approaches for omic data analysis, Armenian Wine Genome Program
Institutions: Armenian Bioinformatics Institute, Interdisciplinary Center for Bioinformatics (IZBI)

Projects: Study of the molecular mechanisms of familial Mediterranean fever using genetic engineering and functional genomics, Development of induced pluripotent stem cell bank of patients with Familial Mediterranean Fever, Molecular Profiling of Cancer Metastases, Sex-specific differences in long-term gamma and simGCRsim-associated alterations in deferential gene expression in the heart tissue, Molecular characterization of cancers with long-read RNA sequencing, ML approaches for omic data analysis, Mental disorders and aging brain, Armenian Wine Genome Program, Functional Genomics of Vine, COVID-19, Genetic History of Armenians, Molecular epidemiology of multi-drug resistance, Multi-Omics Molecular Diversity of Cancers
Institutions: Russian-Armenian University, Institute of Molecular Biology NAS RA

Projects: Mental disorders and aging brain
Institutions: Institute of Molecular Biology NAS RA
Molecular epidemiology of multi-drug resistance focuses on investigating the genetic basis and dissemination of bacteria resistant to multiple antibiotics, with particular attention to resistance mechanisms, outbreak tracking using molecular techniques, and the evolutionary dynamics of resistant strains.
Programme: Genes, Environment and Chronic Diseases
Public web page: Not specified
Organisms: Not specified
Coronavirus disease 2019 (COVID-19) is a contagious disease caused by the coronavirus SARS-CoV-2. In January 2020, the disease spread worldwide, resulting in the COVID-19 pandemic.
Programme: Genes, Environment and Chronic Diseases
Public web page: Not specified
Organisms: Not specified
This project focuses on studies around brain disorders and ageing.
Programme: Genes, Environment and Chronic Diseases
Public web page: Not specified
Organisms: Human
We investigate telomeric fragments in cell-free DNA in blood plasma in disease. We aim to develop novel diagnostic approaches to identify and monitor disease status in cancers and chronic disorders through liquid biopsies.
Programme: Genes, Environment and Chronic Diseases
Public web page: Not specified
Organisms: Human
We develop bioinformatics algorithms and tools to explore the temporal dynamics of microbiome communities in response to environmental perturbations and treatments. We seek to understand the mechanisms through which the direct effects of perturbations propagate via microbial interaction networks, leading to changes in microbiome composition over time.Through application of these techniques we study antibiotic resistance in complex microbial communities, the impact of pesticides on bee gut microbiome ...
Programme: Genes, Environment and Chronic Diseases
Public web page: Not specified
Organisms: Human, Microbiome
This dataset provides data necessary to replicate the results of the time-perturbation analysis of gene expression in health and mental disorders. The corresponding code is available in the GitHub repository under the https://github.com/susieavagyan/BrainExp-TemporalDynamics link.
Creator: Arsen Arakelyan
Submitter: Arsen Arakelyan
Investigations: No Investigations
Studies: No Studies
Assays: No Assays
This dataset provides data necessary to replicate the results of the time-perturbation analysis of gene expression in health and mental disorders. The corresponding code is available in the GitHub repository under the https://github.com/susieavagyan/BrainExp-TemporalDynamics link.
Creator: Arsen Arakelyan
Submitter: Arsen Arakelyan
Investigations: No Investigations
Studies: No Studies
Assays: No Assays
Abstract (Expand)
Authors: A. Stepanyan, A. Arakelyan, J. Schug
Date Published: 24th Mar 2025
Publication Type: Journal
PubMed ID: 40023890
Citation: Environ Int. 2025 Mar;197:109344. doi: 10.1016/j.envint.2025.109344. Epub 2025 Feb 21.
Abstract (Expand)
Authors: Anahit Sedrakyan, Zaruhi Gevorgyan, Magdalina Zakharyan, Karine Arakelova, Shoghik Hakobyan, Alvard Hovhannisyan, Rustam Aminov
Date Published: 9th Jan 2025
Publication Type: Journal
DOI: 10.3390/ijms26020504
Citation: International Journal of Molecular Sciences,26(2):504
Abstract (Expand)
Authors: A. Arakelyan, S. Avagyan, A. Kurnosov, T. Mkrtchyan, G. Mkrtchyan, R. Zakharyan, K. R. Mayilyan, H. Binder
Date Published: 17th Feb 2024
Publication Type: Journal
PubMed ID: 38368435
Citation: Schizophrenia (Heidelb). 2024 Feb 17;10(1):19. doi: 10.1038/s41537-024-00443-7.
Abstract (Expand)
Authors: Arsen Arakelyan, Susanna Avagyan, Aleksey Kurnosov, Tigran Mkrtchyan, Gohar Mkrtchyan, Roksana Zakharyan, Karine R. Mayilyan, Hans Binder
Date Published: 17th Feb 2024
Publication Type: Journal
DOI: 10.1038/s41537-024-00443-7
Citation: Schizophrenia,10(1)
Abstract (Expand)
Authors: Ali El‐Ayoubi, Arsen Arakelyan, Moritz Klawitter, Luisa Merk, Siras Hakobyan, Irene Gonzalez‐Menendez, Leticia Quintanilla Fend, Per Sonne Holm, Wolfgang Mikulits, Matthias Schwab, Lusine Danielyan, Ulrike Naumann
Date Published: 26th Dec 2023
Publication Type: Journal
Citation: Molecular Oncology,18(3):528-546