SEEK ID: https://armlifebank.am/people/4
ORCID:
https://orcid.org/0000-0002-2242-4678
Joined: 2nd Apr 2025
Related items
The Plant Genomics Programme focuses on the comprehensive characterization of plant genetic resources, aiming to understand the factors that shape genetic variation across plant genomes and drive phenotypic diversity in traits of adaptive and economic importance. The research explores the genetic architecture of plant adaptation to changing climatic conditions and investigates the genomic determinants of genetic diversity. A key objective is the integration of multi-omics data into innovative ...
Projects: Functional Genomics of Vine, Armenian Wine Genome Program
Web page: Not specified
This Programme focuses on the development, implementation, and application of bioinformatics tools for the analysis of large-scale genomic datasets. It aims to facilitate the processing, integration, and interpretation of high-throughput sequencing data, including whole-genome, transcriptome, and epigenome analyses. The Programme encompasses computational approaches for variant discovery, gene expression profiling, network biology, and multi-omics data integration.
Projects: Biological pathway activity analysis, ML approaches for omic data analysis, Tools for Telomere Biology
Web page: Not specified
This program is designed to encapsulate and facilitate research projects focusing on the intricate dynamics between genetic predispositions and environmental factors in the progression of chronic diseases, excluding cancer. This initiative aims to unravel the molecular mechanisms and pathways that underlie these diseases, thereby paving the way for targeted interventions and therapies.
Projects: Mental disorders and aging brain, Omics-Based Insights into Human Long-Term Exposure to Environmental Metals
Web page: Not specified
This Programme offers a comprehensive summary of various projects focused on deciphering the intricate molecular mechanisms of cancer development, progression, and response to treatments, utilizing bioinformatics, computational biology, and machine learning. These are multi-laboratory efforts carried out across several research institutions, supported by various grant programs.
Projects: Molecular Profiling of Cancer Metastases, Molecular characterization of cancers with long-read RNA sequencing
Web page: Not specified
Principal Investigator: Prof. Hans Binder
University: University of Leipzig
Research Group: Kristina Margaryan, Maria Nikoghosyan, Tomas Konecny, Anush Baloyan, Hripsime Gasoyan, Emma Hovhannisyan, Levon Galstyan, Duan Shengchang
Duration: 2023-2027
Co-implementing and hosting partner: Armenian Bioinformatics Institute (ABI) and Institute of Molecular Biology
Project Importance The cultivated grape (Vitis vinifera) has become the world’s leading fruit crop. Grape is unique not only because it is ...
Programme: Plant Genomics & Bioinformatics
Public web page: https://www.fast.foundation/en/program/847/2022/new_tab/6586/6677
Organisms: Grapevine
This project focuses on developing and applying machine learning (ML) methodologies to analyze complex omic datasets, including genomics, transcriptomics, proteomics, and metabolomics. By leveraging advanced ML techniques, the project aims to uncover novel biological insights, identify biomarkers, and enhance our understanding of molecular mechanisms underlying various diseases. The initiative is a collaborative effort maintained by the Institute of Molecular Biology NAS RA (IMB), ...
Programme: Bioinformatics Tools for Analysis of Big Genomic Data
Public web page: Not specified
Organisms: Not specified
This project focuses on studies around brain disorders and ageing.
Programme: Genes, Environment and Chronic Diseases
Public web page: Not specified
Organisms: Human
Programme: Bioinformatics Tools for Analysis of Big Genomic Data
Public web page: Not specified
Organisms: Not specified
Together with the scientists at Agenus, a US-based biotech company specializing in innovative forms of cancer treatment, including the discovery and development of immuno-oncology therapies, ABI has formed a team of students and researchers to study cancer metastases and identify potential biomarkers and targets for cancer immunotherapies. This collaboration is also part of our long-term vision of supporting biotech developments in Armenia. The team discovers transcriptomics heterogeneity of Liver ...
Programme: Cancer Omics
Public web page: https://abi.am/research/research-labs/agenus-lab/
Start date: 21st Feb 2024
Organisms: Human
Abstract (Expand)
Authors: M. Hakobyan, H. Binder, A. Arakelyan
Date Published: 2nd Jul 2024
Publication Type: Journal
PubMed ID: 38763334
Citation: J Biol Chem. 2024 Jun;300(6):107392. doi: 10.1016/j.jbc.2024.107392. Epub 2024 May 18.
Abstract (Expand)
Authors: A. Arakelyan, S. Avagyan, A. Kurnosov, T. Mkrtchyan, G. Mkrtchyan, R. Zakharyan, K. R. Mayilyan, H. Binder
Date Published: 17th Feb 2024
Publication Type: Journal
PubMed ID: 38368435
Citation: Schizophrenia (Heidelb). 2024 Feb 17;10(1):19. doi: 10.1038/s41537-024-00443-7.
Abstract (Expand)
Authors: S. Hakobyan, A. Stepanyan, L. Nersisyan, H. Binder, A. Arakelyan
Date Published: 8th Sep 2023
Publication Type: Journal
PubMed ID: 37680201
Citation: Front Genet. 2023 Aug 23;14:1264656. doi: 10.3389/fgene.2023.1264656. eCollection 2023.
Abstract (Expand)
Authors: Maria Nikoghosyan, Henry Loeffler-Wirth, Suren Davidavyan, Hans Binder, Arsen Arakelyan
Date Published: 27th Dec 2021
Publication Type: Journal
DOI: 10.3390/biomedinformatics2010004
Citation: BioMedInformatics,2(1):62-76
Abstract (Expand)
Authors: L. Nersisyan, A. Simonyan, H. Binder, A. Arakelyan
Date Published: 26th Apr 2021
Publication Type: Journal
PubMed ID: 33897770
Citation: Front Genet. 2021 Apr 7;12:662464. doi: 10.3389/fgene.2021.662464. eCollection 2021.