SEEK ID: https://armlifebank.am/people/5
Location:
Armenia
ORCID:
https://orcid.org/0009-0009-7992-1366
Joined: 21st Feb 2024
Expertise: Genetics, Molecular Biology
Tools: PCR, Sequencing, qtPCR, rtPCR
Roles
Admin
Project administrator
- Study of the molecular mechanisms of familial Mediterranean fever using genetic engineering and functional genomics
- Development of induced pluripotent stem cell bank of patients with Familial Mediterranean Fever
- Molecular Profiling of Cancer Metastases
- Sex-specific differences in long-term gamma and simGCRsim-associated alterations in differential gene expression in the heart tissue
- Molecular characterization of cancers with long-read RNA sequencing
- ML approaches for omic data analysis
- Mental disorders and aging brain
- Armenian Wine Genome Program
- Functional Genomics of Vine
- COVID-19
- Molecular epidemiology of multi-drug resistance
- Multi-Omics Molecular Diversity of Cancers
- Third International Congress "CRISPR-2025"
- International Summit in Immuno-Oncology
- Low dose radiation risks: present research and future perspectives
- Whole genome and whole exome sequencing based analysis of diversity of genomic variants in Armenian population
Programme administrator
Their tagsRelated items
- Programmes (9)
- Projects (20)
- Institutions (2)
- Data files (12)
- Publications (101)
- Presentations (30)
- Events (2)
- Documents (3)
- Sample types (1)
- Samples (4)
- Collections (3)
Principal Investigator: Prof. David Goukassian
University: Icahn School of Medicine at Mount Sinai
Duration:2023-2027
Hosting partner: Institute of Molecular Biology NAS RA (IMB)
Project Importance The high likelihood of developing genomic instability due to exposure to ionizing radiation suggests that exposure can cause DNA damage to hematopoietic stem cells (HSCs), promoting the development of somatic mutations that can lead to aberrant clonal events. Thus, it is conceivable that space ...
Web page: https://fast.foundation/en/program/847/2022/new_tab/6586/7014
This program is dedicated to the discovery and study of new antiviral drugs against human and animal viruses, including influenza A and B, herpes simplex virus type 1, and African swine fever virus. Computational methods and in vitro assays are combined to identify new antiviral agents. The mechanism of action of the most promising compounds is studied using various cellular approaches.
Projects: Discovery of new antiviral compounds by combining in silico and in vitro methods, MAPK/ERK pathway inhibitors as novel antiviral compounds, African swine fever virus
Web page: Not specified
The Armenian Genome Project aims at unraveling our genetic background and bringing personalized and precision medicine to Armenia
Projects: Genetic History of Armenians, Whole genome and whole exome sequencing based analysis of diversity of genomic variants in Armenian population
Web page: http://armeniangenome.am/
This Programme sumarizes scientific events and associated documents.
Projects: Low dose radiation risks: present research and future perspectives, Third International Congress "CRISPR-2025", International Summit in Immuno-Oncology, Molecular Diagnostics in Oncology and Related Fields of Medicine
Web page: Not specified
The Plant Genomics Programme focuses on the comprehensive characterization of plant genetic resources, aiming to understand the factors that shape genetic variation across plant genomes and drive phenotypic diversity in traits of adaptive and economic importance. The research explores the genetic architecture of plant adaptation to changing climatic conditions and investigates the genomic determinants of genetic diversity. A key objective is the integration of multi-omics data into innovative ...
Projects: Functional Genomics of Vine, Armenian Wine Genome Program
Web page: Not specified
Space radiation (IR) from Solar Particle Events (SPE) and Galactic Cosmic Rays (GCR), also known as high charge and energy (HZE) IR, is a primary risk associated with deep-space missions. There are limited animal and human studies on the risk of cardiovascular disease (CVD) development due to space-IR. The cardiac effects induced by space-type IR, specifically simplified GCR simulated (simGCRsim)-IR, are yet to be discovered. We hypothesized that gamma (γ) and simGCRsim IR-induced biological ...
Programme: Space Radiobiology
Public web page: Not specified
Start date: 1st Jul 2023
End date: 30th Jun 2027
Organisms: Mouse
An increasing number of countries are investing efforts to exploit the human genome, in order to improve genetic diagnostics and to pave the way for the integration of precision medicine into health systems. The expected benefits include improved understanding of normal and pathological genomic variation, shorter time-to-diagnosis, cost-effective diagnostics, targeted prevention and treatment, and research advances. Despite the significance of such studies, there is a lack of comprehensive genomic ...
Programme: Armenian Genome Project
Public web page: Not specified
Start date: 1st Sep 2024
End date: 1st Jun 2028
Organisms: Not specified
Programme: Antiviral Drugs
Public web page: Not specified
Organisms: Not specified
We have done a chemoinformatics analysis of more than 400,000 chemical compounds tested against human influenza A and B viruses, in which we showed the distribution of various chemical and physicochemical properties in relation to the antiviral activity of the compounds. We also identified compounds that demonstrated activity against the virus, but whose derivatives remain unstudied and therefore may serve as subjects for future research. We have also submitted another manuscript describing a new ...
Programme: Antiviral Drugs
Public web page: Not specified
Organisms: Not specified
We invite you to take part in the Annual Scientific and Practical Conference of the Interregional Public Organization of Molecular Geneticists in Oncology and Oncohematology (IPO MGO)
“Molecular Diagnostics in Oncology and Related Fields of Medicine,” which will be held on January 17–18, 2026, in Yerevan, Armenia.
The first IPO MGO conference was held in Yekaterinburg in 2022, the second in Saint Petersburg in 2023, and the third in Nizhny Novgorod in 2024. Each event brought together a large ...
Programme: Events
Public web page: https://imb.am/mgdc2026/
Start date: 17th Jan 2026
End date: 18th Jan 2026
Organisms: Not specified
Genotype data produced by HaplotypeCaller and Illumina genotyping datа
Creator: Anahit Hovhannisyan
Submitter: Lana Karapetyan
Investigations: No Investigations
Studies: No Studies
Assays: No Assays
Links to Individual Files in the Dataset
This study included 299 SARS-CoV-2 infected patients. During April-May 2020, blood and nasopharyngeal swab samples from patients were collected in six hospitals of the Health Ministry of the Republic of Armenia: National Center for Infection Diseases, Surb Grigor Lusavorich, Surb Astvatsamayr and Artashat Medical Centres, Maralik and Akhuryan Mother and Child Health Centers. The diagnosis was performed on nasopharyngeal specimens by detection of SARS-CoV-2 ...
Creator: Anahit Hovhannisyan
Submitter: Lana Karapetyan
Investigations: No Investigations
Studies: No Studies
Assays: No Assays
Datasets for Publication
Creators: None
Submitter: Lana Karapetyan
Investigations: No Investigations
Studies: No Studies
Assays: No Assays
Sequencing of SARS-CoV-2 provides essential information on viral evolution, transmission, and epidemiology. In this study, we performed whole-genome sequencing of SARS-CoV-2 using nanopore and Illumina short-read sequencing to describe the circulation of the virus lineage in Armenia.
This dataset contains Nextstrain configuration files, the auspice JSON file, BEAST output logs, and trees files, and resulting log and tree files as well as R scripts and data files used in phylogenetic and functional ...
Creators: Arsen Arakelyan, Diana Avetyan
Submitter: Lana Karapetyan
Investigations: No Investigations
Studies: No Studies
Assays: No Assays
Aligned sequencing data is available in the NCBI Sequence Read Archive (SRA, https://www.ncbi.nlm.nih.gov/sra/) under accession SRP095082. Variants were called using GATK HaplotypeCaller (version 3.6). After joint performing joint genotyping multi-sample vcf file was generated. Next, SNPs and indels were extracted into two different vcf files and specific set of filters were applied for each case.
Creator: Arsen Arakelyan
Submitter: Lana Karapetyan
Investigations: No Investigations
Studies: No Studies
Assays: No Assays
Abstract (Expand)
Authors: Roksana Zakharyan, Ani Stepanyan, Arpine Minasyan, Suren Davitavyan, Gisane Lazaryan, Siras Hakobyan, Agnieszka Brojakowska, Malik Bisserier, Susmita Sahoo, Shihong Zhang, Venkata Naga Srikanth Garikipati, Mary K. Khlgatian, Arsen Arakelyan, David A. Goukassian
Date Published: 23rd Apr 2026
Publication Type: Journal
DOI: 10.1007/s40778-026-00255-8
Citation: Current Stem Cell Reports,12(1)
Abstract (Expand)
Authors: Irina Tirosyan, Yeva Gabrielyan, Vahe Petrosyan, Marco Vignuzzi, Hovakim Zakaryan
Date Published: 22nd Mar 2026
Publication Type: Journal
Abstract (Expand)
Authors: Smbat Gevorgyan, Marusya Ayvazyan, Levon Kharatyan, Anastasiya Shavina, Narek Abelyan, Hamlet Khachatryan, Hovakim Zakaryan
Date Published: 10th Mar 2026
Publication Type: Journal
Abstract (Expand)
Authors: Maria Nikoghosyan, Emma Hovhannisyan, Nate Zadirako, Shengchang Duan, Armine Asatryan, Arsen Arakelyan, Kristine Margaryan, Anush Baloyan, Tomas Konecny, Hans Binder
Date Published: 11th Feb 2026
Publication Type: Journal
DOI: 10.1186/s12870-026-08287-2
Citation: BMC Plant Biology
Abstract (Expand)
Authors: Gohar Mkrtchyan, Kristina Avanesyan, Hovsep Ghazaryan, Merry Mazmanian, Marie-Alexandra Alyanakian, Arsene Mekinian, Arsen Arakelyan
Date Published: 13th Jan 2026
Publication Type: Journal
DOI: 10.3389/fpubh.2025.1749588
Citation: Frontiers in Public Health,13
Evgeny Imyanitov
Ethnic Aspects of Medical Genetics: Hereditary Tumor Syndromes
N.N. Petrov National Medical Research Center of Oncology, Saint Petersburg, Russian Federation
10:30 - 10:50
Moderators: R. Zakharyan, M. Filipenko
Section 1
Creator: Evgeny Imyanitov
Submitter: Lana Karapetyan
Vladislav Mileiko
Experience with NGS Testing in Practice: From Clinical Challenges to Scientific Discoveries
"Oncoatlas", Moscow, Russian Federation
17:40 - 17:50
Moderators: A. Arakelyan, A. Tsukanov
Section 4
Creator: Vladislav Mileiko
Submitter: Lana Karapetyan
Alena Osipova
Investigation of HRR Genes in Tumor Samples from Patients with Metastatic Prostate Cancer
A.S. Loginov Moscow Clinical Scientific Center, Moscow, Russian Federation
17:20 - 17:40
Moderators: A. Arakelyan, A. Tsukanov
Section 4
Creator: Alena Osipova
Submitter: Lana Karapetyan
Elena Kolesnikova
Personalized Therapy in Oncology – Myth or Reality? Experience of a Regional Center
Regional Oncology Dispensary, Nizhny Novgorod, Russian Federation
17:00 - 17:20
Moderators: A. Arakelyan, A. Tsukanov
Section 4
Creator: Elena Kolesnikova
Submitter: Lana Karapetyan
Anton Pushkin
Current Russian Developments in Molecular Oncogenetics
"Sintol", Moscow, Russian Federation
16:20 - 16:40
Moderators: G. Martirosyan, T. Kekeeva
Section 3
Creator: Anton Pushkin
Submitter: Lana Karapetyan
We invite you to take part in the Annual Scientific and Practical Conference of the Interregional Public Organization of Molecular Geneticists in Oncology and Oncohematology (IPO MGO) “Molecular Diagnostics in Oncology and Related Fields of Medicine”, which will be held on January 17–18, 2026, in Yerevan, Armenia.
Start Date: 17th Jan 2026 (17th Jan 2026 (Asia/Yerevan))
End Date: 18th Jan 2026 (18th Jan 2026 (Asia/Yerevan))
Event Website: https://imb.am/mgdc2026/
Country:
Armenia
City: Yerevan
We are pleased to invite your specialists to the International Summit in Immuno-Oncology, which will take place in Yerevan, Armenia, on October 16–18, 2025, organized by Santé Arménie in collaboration with Inserm, the Armenian Association of Clinical Pathologists and Cytologists, and the Institute of Molecular Biology.
This summit marks the beginning of an ambitious effort to establish a world-class immuno-oncology ecosystem in Armenia. We are gathering leading experts in cancer research, clinical ...
Start Date: 16th Oct 2025 (16th Oct 2025 (Asia/Yerevan))
End Date: 18th Oct 2025 (18th Oct 2025 (Asia/Yerevan))
Event Website: Not specified
Country:
Armenia
City: Yerevan
Molecular Diagnostics in Oncology and Related Fields of Medicine
Date: January 17–18, 2026, Yerevan, Armenia
Creator: Arsen Arakelyan
Submitter: Lana Karapetyan
Investigations: No Investigations
Studies: No Studies
Assays: No Assays
16-18 OCTOBER 2025 YEREVAN, ARMENIA
AGENDA
Creators: Lana Karapetyan, Arsen Arakelyan
Submitter: Lana Karapetyan
Investigations: No Investigations
Studies: No Studies
Assays: No Assays
- Cell Technologies
- Regenerative Medicine
- Intelligent Data Science
- Synthetic Biology
- Postgenome
- Research & Development
OCTOBER 5-10, 2025 YEREVAN, ARMENIA
Creators: Lana Karapetyan, Arsen Arakelyan
Submitter: Lana Karapetyan
Investigations: No Investigations
Studies: No Studies
Assays: No Assays
Patient-specific induced pluripotent stem cells (iPSCs) are reprogrammed somatic cells derived from individual patients through the expression of key transcription factors (e.g., OCT4, SOX2, KLF4, and c-MYC). These cells exhibit pluripotency, allowing them to differentiate into various cell types and serve as in vitro models for studying disease mechanisms, drug screening, and regenerative medicine.
Sample Name (String) *, Type (String) *, Condition (String) *, Link (String) , Location (String)
Not specified
Type: Patient-specific induced pluripotent stem cells (iPSCs)
Creators: Arsen Arakelyan, Lana Karapetyan, Roksana Zakharyan
Submitter: Arsen Arakelyan
Type: Patient-specific induced pluripotent stem cells (iPSCs)
Creators: Arsen Arakelyan, Lana Karapetyan, Roksana Zakharyan
Submitter: Arsen Arakelyan
Type: Patient-specific induced pluripotent stem cells (iPSCs)
Creators: Arsen Arakelyan, Lana Karapetyan, Roksana Zakharyan
Submitter: Arsen Arakelyan
Type: Patient-specific induced pluripotent stem cells (iPSCs)
Creators: Arsen Arakelyan, Lana Karapetyan, Roksana Zakharyan
Submitter: Arsen Arakelyan
The archive contains presentation slides and recorded talks from the Third International Congress "CRISPR-2025".
The archive contains presentation slides and recorded talks from the "International Summit in Immuno-Oncology".
The archive contains presentation slides and recorded talks from the conference "Molecular Diagnostics in Oncology and Related Fields of Medicine".
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