SEEK ID: https://armlifebank.am/people/5
Location: Armenia
ORCID: Not specified
Joined: 21st Feb 2024
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Disorders within the cells, the fundamental building blocks of life, lie at the core of all human diseases. This program provides information on various projects aimed at improving human health, possibly as diagnostic, preventive or curative therapies. These are collaborations with several research institutes supported by various grant programs.
Web page: Not specified
In this project genetic engineering and functional genomics approaches will be used to describe molecular mechanisms of FMF. Using DNA/RNA samples obtained from FMF patients and healthy subjects MEFV nanopore gene sequencing will be performed to identify genetic variants and possibly find novel putative functional variants. The impact of genetic variants on transcriptome landscape will be studies by RNA-sequencing using nanopore sequencing device. Based on MEFV sequencing data and patients clinical ...
Programme: Cellular basis of diseases
Public web page: Not specified
Start date: 1st Sep 2021
End date: 31st Aug 2024
Organisms: Human
Abstract (Expand)
Authors: Varduhi Hayrapetyan, Lana Karapetyan, Lilit Ghukasyan, Sofi Atshemyan, Hovsep Ghazaryan, Valentina Vardanyan, Vahan Mukuchyan, Arsen Arakelyan, Roksana Zakharyan
Date Published: 2nd Dec 2024
Publication Type: Journal
Citation: International Journal of Molecular Sciences,25(23):12958
Abstract (Expand)
Authors: Lilit Ghukasyan, Gisane Khachatryan, Tamara Sirunyan, Arpine Minasyan, Siras Hakobyan, Andranik Chavushyan, Varduhi Hayrapetyan, Hovsep Ghazaryan, Gevorg Martirosyan, Gohar Mkrtchyan, Valentina Vardanyan, Vahan Mukuchyan, Ashot Davidyants, Roksana Zakharyan, Arsen Arakelyan
Date Published: 29th Nov 2024
Publication Type: Journal
DOI: 10.3389/fgene.2024.1493295
Citation: Frontiers in Genetics,15
Abstract (Expand)
Authors: Elena V. Grigor’eva, Lana V. Karapetyan, Anastasia A. Malakhova, Sergey P. Medvedev, Julia M. Minina, Varduhi H. Hayrapetyan, Valentina S. Vardanyan, Suren M. Zakian, Arsen Arakelyan, Roksana Zakharyan
Date Published: 1st Jun 2024
Publication Type: Journal
DOI: 10.3390/ijms25116102
Citation: International Journal of Molecular Sciences,25(11):6102
Abstract (Expand)
Authors: Elena V. Grigor’eva, Anastasia A. Malakhova, Lilit Ghukasyan, Varduhi Hayrapetyan, Sofi Atshemyan, Valentina Vardanyan, Suren M. Zakian, Roksana Zakharyan, Arsen Arakelyan
Date Published: No date defined
Publication Type: Journal
DOI: 10.1016/j.scr.2023.103147
Citation: Stem Cell Research,71:103147