Russian-Armenian University

This programme aims to implement genomic epidemiology approaches to characterize the genetic determinants of antimicrobial resistance, identify transmission pathways, and monitor the dissemination of high-risk bacterial clones across healthcare settings in Armenia. Using whole-genome sequencing (WGS), bioinformatics analyses, and integration of epidemiological data, the project will investigate the priority drug-resistant pathogens associated with the spread of difficult-to-treat infections in ...

Principal Investigator: Prof. David Goukassian

University: Icahn School of Medicine at Mount Sinai

Duration:2023-2027

Hosting partner: Institute of Molecular Biology NAS RA (IMB)

Project Importance The high likelihood of developing genomic instability due to exposure to ionizing radiation suggests that exposure can cause DNA damage to hematopoietic stem cells (HSCs), promoting the development of somatic mutations that can lead to aberrant clonal events. Thus, it is conceivable that space ...

This program is dedicated to the discovery and study of new antiviral drugs against human and animal viruses, including influenza A and B, herpes simplex virus type 1, and African swine fever virus. Computational methods and in vitro assays are combined to identify new antiviral agents. The mechanism of action of the most promising compounds is studied using various cellular approaches.

The Armenian Genome Project aims at unraveling our genetic background and bringing personalized and precision medicine to Armenia

This Programme sumarizes scientific events and associated documents.

Molecular epidemiology of multi-drug resistance focuses on investigating the genetic basis and dissemination of bacteria resistant to multiple antibiotics, with particular attention to resistance mechanisms, outbreak tracking using molecular techniques, and the evolutionary dynamics of resistant strains.

Principal Investigator: Prof. Hans Binder

University: University of Leipzig

Research Group: Kristina Margaryan, Maria Nikoghosyan, Tomas Konecny, Anush Baloyan, Hripsime Gasoyan, Emma Hovhannisyan, Levon Galstyan, Duan Shengchang

Duration: 2023-2027

Co-implementing and hosting partner: Armenian Bioinformatics Institute (ABI) and Institute of Molecular Biology

Project Importance The cultivated grape (Vitis vinifera) has become the world’s leading fruit crop. Grape is unique not only because it is ...

Together with the scientists at Agenus, a US-based biotech company specializing in innovative forms of cancer treatment, including the discovery and development of immuno-oncology therapies, ABI has formed a team of students and researchers to study cancer metastases and identify potential biomarkers and targets for cancer immunotherapies. This collaboration is also part of our long-term vision of supporting biotech developments in Armenia. The team discovers transcriptomics heterogeneity of Liver ...

This project focuses on developing and applying machine learning (ML) methodologies to analyze complex omic datasets, including genomics, transcriptomics, proteomics, and metabolomics. By leveraging advanced ML techniques, the project aims to uncover novel biological insights, identify biomarkers, and enhance our understanding of molecular mechanisms underlying various diseases. The initiative is a collaborative effort maintained by the Institute of Molecular Biology NAS RA (IMB), ...