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Projects: Sex-specific differences in long-term gamma and simGCRsim-associated alterations in deferential gene expression in the heart tissue, Functional Genomics of Vine, Molecular Profiling of Cancer Metastases, Omics-Based Insights into Human Long-Term Exposure to Environmental Metals, Biological pathway activity analysis, ML approaches for omic data analysis, Tools for Telomere Biology, Mental disorders and aging brain, Armenian Wine Genome Program, Study of the molecular mechanisms of familial Mediterranean fever using genetic engineering and functional genomics, Molecular characterization of cancers with long-read RNA sequencing, Low dose radiation risks: present research and future perspectives, Third International Congress "CRISPR-2025", International Summit in Immuno-Oncology, Molecular Diagnostics in Oncology and Related Fields of Medicine, Discovery of new antiviral compounds by combining in silico and in vitro methods, African swine
Institutions: Institute of Molecular Biology NAS RA, Armenian Bioinformatics Institute
https://orcid.org/0000-0002-6851-1056
Projects: Biological pathway activity analysis, Sex-specific differences in long-term gamma and simGCRsim-associated alterations in deferential gene expression in the heart tissue, ML approaches for omic data analysis, Molecular characterization of cancers with long-read RNA sequencing
Institutions: Institute of Molecular Biology NAS RA
https://orcid.org/0000-0002-6875-2482
Expertise: Bioinformatics
Tools: Cytoscape, Genomics, Microarray analysis, Python, R, Single Cell analysis, Transcriptomics
Siras Hakobyan is currently a Junior Researcher and PhD student in the Research Group of Bioinformatics at the Institute of Molecular Biology NAS RA in Yerevan, Armenia. He received his Master's and Bachelor's degrees in Bioinformatics from Yerevan State University, completing his studies in 2018 and 2016. His PhD project focuses on pathway-centered analysis of high-throughput omics data, particularly examining pathway activity states in cancers based on pathway topology, gene expression, and ...
This program is dedicated to the discovery and study of new antiviral drugs against human and animal viruses, including influenza A and B, herpes simplex virus type 1, and African swine fever virus. Computational methods and in vitro assays are combined to identify new antiviral agents. The mechanism of action of the most promising compounds is studied using various cellular approaches.
Projects: Discovery of new antiviral compounds by combining in silico and in vitro methods, MAPK/ERK pathway inhibitors as novel antiviral compounds, African swine
Web page: Not specified
The Armenian Genome Project aims at unraveling our genetic background and bringing personalized and precision medicine to Armenia
Projects: Genetic History of Armenians, Whole genome and whole exome sequencing based analysis of diversity of genomic variants in Armenian population
Web page: http://armeniangenome.am/
This Programme sumarizes scientific events and associated documents.
Projects: Low dose radiation risks: present research and future perspectives, Third International Congress "CRISPR-2025", International Summit in Immuno-Oncology, Molecular Diagnostics in Oncology and Related Fields of Medicine
Web page: Not specified
The Plant Genomics Programme focuses on the comprehensive characterization of plant genetic resources, aiming to understand the factors that shape genetic variation across plant genomes and drive phenotypic diversity in traits of adaptive and economic importance. The research explores the genetic architecture of plant adaptation to changing climatic conditions and investigates the genomic determinants of genetic diversity. A key objective is the integration of multi-omics data into innovative ...
Projects: Functional Genomics of Vine, Armenian Wine Genome Program
Web page: Not specified
This Programme focuses on the development, implementation, and application of bioinformatics tools for the analysis of large-scale genomic datasets. It aims to facilitate the processing, integration, and interpretation of high-throughput sequencing data, including whole-genome, transcriptome, and epigenome analyses. The Programme encompasses computational approaches for variant discovery, gene expression profiling, network biology, and multi-omics data integration.
Projects: Biological pathway activity analysis, ML approaches for omic data analysis, Tools for Telomere Biology
Web page: Not specified
Programme: Antiviral Drugs
Public web page: Not specified
Organisms: Not specified
We have done a chemoinformatics analysis of more than 400,000 chemical compounds tested against human influenza A and B viruses, in which we showed the distribution of various chemical and physicochemical properties in relation to the antiviral activity of the compounds. We also identified compounds that demonstrated activity against the virus, but whose derivatives remain unstudied and therefore may serve as subjects for future research. We have also submitted another manuscript describing a new ...
Programme: Antiviral Drugs
Public web page: Not specified
Organisms: Not specified
An increasing number of countries are investing efforts to exploit the human genome, in order to improve genetic diagnostics and to pave the way for the integration of precision medicine into health systems. The expected benefits include improved understanding of normal and pathological genomic variation, shorter time-to-diagnosis, cost-effective diagnostics, targeted prevention and treatment, and research advances. Despite the significance of such studies, there is a lack of comprehensive genomic ...
Programme: Armenian Genome Project
Public web page: Not specified
Start date: 1st Sep 2024
End date: 1st Jun 2028
Organisms: Not specified
We invite you to take part in the Annual Scientific and Practical Conference of the Interregional Public Organization of Molecular Geneticists in Oncology and Oncohematology (IPO MGO)
“Molecular Diagnostics in Oncology and Related Fields of Medicine,” which will be held on January 17–18, 2026, in Yerevan, Armenia.
The first IPO MGO conference was held in Yekaterinburg in 2022, the second in Saint Petersburg in 2023, and the third in Nizhny Novgorod in 2024. Each event brought together a large ...
Programme: Events
Public web page: https://imb.am/mgdc2026/
Start date: 17th Jan 2026
End date: 18th Jan 2026
Organisms: Not specified
The “Low dose radiation risks: present research and future perspectives” Advanced Research Workshop is a NATO (North Atlantic Treaty Organization)-sponsored workshop organized by the McMaster University (Canada) and Institute of Molecular Biology NAS RA (National Academy of Sciences of Republic of Armenia) which offers a unique opportunity to learn about new discoveries and exchange experience with professionals in the field of radioecology, radiobiology, country-specific regulatory agencies, ...
Programme: Events
Public web page: https://imb.am/rad2025/
Start date: 30th Mar 2025
End date: 2nd Apr 2025
Organisms: Not specified
