Genomic Tracking of Antimicrobial Resistance in Armenia
This programme aims to implement genomic epidemiology approaches to characterize the genetic determinants of antimicrobial resistance, identify transmission pathways, and monitor the dissemination of high-risk bacterial clones across healthcare settings in Armenia. Using whole-genome sequencing (WGS), bioinformatics analyses, and integration of epidemiological data, the project will investigate the priority drug-resistant pathogens associated with the spread of difficult-to-treat infections in Armenia. The generated data will provide critical insights into the evolution and spread of antimicrobial resistance in Armenia, helping public health authorities develop targeted interventions to reduce the burden of drug-resistant infections. Current research activity: i) in-depth characterization of the key bacterial pathogens associated with the spread of difficult-to-treat infections in Armenia to improve antimicrobial therapy approaches; ii) isolation of new bacteriophages that are active against multidrug-resistant bacterial pathogens to develop alternative or complementary treatment options for drug-resistant infections.
Web page: Not specified
Funding details: Related items
Projects: Sex-specific differences in long-term gamma and simGCRsim-associated alterations in differential gene expression in the heart tissue, Functional Genomics of Vine, Molecular Profiling of Cancer Metastases, Omics-Based Insights into Human Long-Term Exposure to Environmental Metals, Biological pathway activity analysis, ML approaches for omic data analysis, Tools for Telomere Biology, Mental disorders and aging brain, Armenian Wine Genome Program, Study of the molecular mechanisms of familial Mediterranean fever using genetic engineering and functional genomics, Molecular characterization of cancers with long-read RNA sequencing, Low dose radiation risks: present research and future perspectives, Third International Congress "CRISPR-2025", International Summit in Immuno-Oncology, Molecular Diagnostics in Oncology and Related Fields of Medicine, Discovery of new antiviral compounds by combining in silico and in vitro methods, African swine fever virus, Whole genome and whole exome sequencing based analysis of diversity of genomic variants in Armenian population
Institutions: Institute of Molecular Biology NAS RA, Armenian Bioinformatics Institute
https://orcid.org/0000-0002-6851-1056
Projects: Study of the molecular mechanisms of familial Mediterranean fever using genetic engineering and functional genomics, Development of induced pluripotent stem cell bank of patients with Familial Mediterranean Fever, Molecular Profiling of Cancer Metastases, Sex-specific differences in long-term gamma and simGCRsim-associated alterations in differential gene expression in the heart tissue, Molecular characterization of cancers with long-read RNA sequencing, ML approaches for omic data analysis, Mental disorders and aging brain, Armenian Wine Genome Program, Functional Genomics of Vine, COVID-19, Genetic History of Armenians, Molecular epidemiology of multi-drug resistance, Multi-Omics Molecular Diversity of Cancers, Third International Congress "CRISPR-2025", International Summit in Immuno-Oncology, Low dose radiation risks: present research and future perspectives, Molecular Diagnostics in Oncology and Related Fields of Medicine, Whole genome and whole exome sequencing based analysis of diversity of genomic variants in Armenian population, Discovery of new antiviral compounds by combining in silico and in vitro methods, African swine fever virus, Microbiota, Inflammation, Metabolic Changes in Infectious and Autoinflammatory Diseases
Institutions: Russian-Armenian University, Institute of Molecular Biology NAS RA
https://orcid.org/0009-0009-7992-1366
Molecular epidemiology of multi-drug resistance focuses on investigating the genetic basis and dissemination of bacteria resistant to multiple antibiotics, with particular attention to resistance mechanisms, outbreak tracking using molecular techniques, and the evolutionary dynamics of resistant strains.
Programme: Genomic Tracking of Antimicrobial Resistance in Armenia
Public web page: Not specified
Abstract (Expand)
Authors: Zaven Karalyan, Anahit Sedrakyan, Karine Arakelova, Magdalina Zakharyan, Shoghik Hakobyan, Sona Hakobyan, Aida Avetisyan, Nane Bayramyan, Hranush Arzumanyan, Vahagn Gevorgyan, Tigranuhi Vardanyan, Bagrat Baghdasaryan, Alexander Karalyan, Lina Hakobyan, Arpine Poghosyan, Liana Abroyan, Elena Karalova, Henry Voskanyan, Zara Semerjyan, Elina Arakelova, Hranush Avagyan
Date Published: 16th May 2026
Publication Type: Journal
Abstract (Expand)
Authors: Anahit Sedrakyan, Zaruhi Gevorgyan, Magdalina Zakharyan, Karine Arakelova, Shoghik Hakobyan, Alvard Hovhannisyan, Rustam Aminov
Date Published: 9th Jan 2025
Publication Type: Journal
Abstract (Expand)
Authors: Anahit Sedrakyan, Zhanna Ktsoyan, Karine Arakelova, Zaruhi Gevorgyan, Magdalina Zakharyan, Shoghik Hakobyan, Alvard Hovhannisyan, Arsen Arakelyan, Rustam Aminov
Date Published: 18th Aug 2022
Publication Type: Journal
Abstract (Expand)
Authors: Anahit M. Sedrakyan, Zhanna A. Ktsoyan, Karine A. Arakelova, Magdalina K. Zakharyan, Alvard I. Hovhannisyan, Zaruhi U. Gevorgyan, Armine A. Mnatsakanyan, Elene G. Kakabadze, Khatuna B. Makalatia, Nina A. Chanishvili, Jean-Paul Pirnay, Arsen A. Arakelyan, Rustam I. Aminov
Date Published: 22nd Dec 2020
Publication Type: Journal
Abstract (Expand)
Authors: Khatuna Makalatia, Elene Kakabadze, Jeroen Wagemans, Nino Grdzelishvili, Nata Bakuradze, Gulnara Natroshvili, Nino Macharashvili, Anahit Sedrakyan, Karine Arakelova, Zhanna Ktsoyan, Magdalina Zakharyan, Zaruhi Gevorgyan, Armine Mnatsakanyan, Farida Tishkova, Cédric Lood, Dieter Vandenheuvel, Rob Lavigne, Jean-Paul Pirnay, Daniel De Vos, Nina Chanishvili, Maia Merabishvili
Date Published: 10th Dec 2020
Publication Type: Journal
