Whole genome and whole exome sequencing based analysis of diversity of genomic variants in Armenian population

An increasing number of countries are investing efforts to exploit the human genome, in order to improve genetic diagnostics and to pave the way for the integration of precision medicine into health systems. The expected benefits include improved understanding of normal and pathological genomic variation, shorter time-to-diagnosis, cost-effective diagnostics, targeted prevention and treatment, and research advances. Despite the significance of such studies, there is a lack of comprehensive genomic data on the Armenian population. Thus, the project’s objective is to explore the genomic variability of the Armenian population by analyzing whole genome sequences (WGS) and whole exome sequences (WES) from various regions in Armenia. We will use the developed bioinformatics pipeline for data analysis and describe the overall landscape of genomic variations with emphasis on genomic variants that are associated with genetic disorders or contributing to risks for complex diseases in the Armenian population.