Antiviral agents against African swine fever virus.
View Publication On PubMed
Export 
BiBTeXAfrican swine fever virus (ASFV) is a significant transboundary virus that continues to spread outside Africa in Europe and most recently to China, Vietnam and Cambodia. Pigs infected with highly virulent ASFV develop a hemorrhagic fever like illness with high lethality reaching up to 100%. There are no vaccines or antiviral drugs available for the prevention or treatment of ASFV infections. We here review molecules that have been reported to inhibit ASFV replication, either as direct-acting antivirals or host-targeting drugs as well as those that act via a yet unknown mechanism. Prospects for future antiviral research against ASFV are also discussed.
SEEK ID: https://armlifebank.am/publications/134
PubMed ID: 31325472
DOI: 10.1016/j.virusres.2019.197669
Projects: African swine
Publication type: Journal
Journal: Virus research
Export PNG
Download
SubmitterViews: 15
Created: 6th May 2026 at 08:33
AttributionsNone
Related items
Projects: Study of the molecular mechanisms of familial Mediterranean fever using genetic engineering and functional genomics, Development of induced pluripotent stem cell bank of patients with Familial Mediterranean Fever, Molecular Profiling of Cancer Metastases, Sex-specific differences in long-term gamma and simGCRsim-associated alterations in deferential gene expression in the heart tissue, Molecular characterization of cancers with long-read RNA sequencing, ML approaches for omic data analysis, Mental disorders and aging brain, Armenian Wine Genome Program, Functional Genomics of Vine, COVID-19, Genetic History of Armenians, Molecular epidemiology of multi-drug resistance, Multi-Omics Molecular Diversity of Cancers, Third International Congress "CRISPR-2025", International Summit in Immuno-Oncology, Low dose radiation risks: present research and future perspectives, Molecular Diagnostics in Oncology and Related Fields of Medicine, Whole genome and whole exome sequencing based analysis of diversity of genomic variants in Armenian population, Discovery of new antiviral compounds by combining in silico and in vitro methods, African swine
Institutions: Russian-Armenian University, Institute of Molecular Biology NAS RA
https://orcid.org/0009-0009-7992-1366
This program is dedicated to the discovery and study of new antiviral drugs against human and animal viruses, including influenza A and B, herpes simplex virus type 1, and African swine fever virus. Computational methods and in vitro assays are combined to identify new antiviral agents. The mechanism of action of the most promising compounds is studied using various cellular approaches.
Projects: Discovery of new antiviral compounds by combining in silico and in vitro methods, MAPK/ERK pathway inhibitors as novel antiviral compounds, African swine
Web page: Not specified
Programme: Antiviral Drugs
Public web page: Not specified
