Projects

The aim of this project is to establish a bank of induced pluripotent stem cells from patients with Familial Mediterranean Fever (FMF) using cell reprogramming approaches for a more comprehensive study of disease molecular mechanisms. In Armenia, FMF prevalence is about 14-100 per 10,000 inhabitants, depending on the region. For the comprehensive research of the disease, it is necessary to have appropriate cell platforms that will contain pathogenic mutations of the FMF. Created stem cell bank ...

The “Low dose radiation risks: present research and future perspectives” Advanced Research Workshop is a NATO (North Atlantic Treaty Organization)-sponsored workshop organized by the McMaster University (Canada) and Institute of Molecular Biology NAS RA (National Academy of Sciences of Republic of Armenia) which offers a unique opportunity to learn about new discoveries and exchange experience with professionals in the field of radioecology, radiobiology, country-specific regulatory agencies, ...

Long-term environmental exposure to metals leads to epigenetic changes and may increase risks to human health. The human epidemiologic and the toxicologic animal model studies provide strong evidence of metal exposure related DNA methylation changes, and, consequently alterations in gene expression, in metabolic, genetic and signal transduction pathways and their functions. The current study is designed to investigate genome wide DNA methylation and transcriptomic changes induced by human chronic ...