Programmes

This Programme focuses on the development, implementation, and application of bioinformatics tools for the analysis of large-scale genomic datasets. It aims to facilitate the processing, integration, and interpretation of high-throughput sequencing data, including whole-genome, transcriptome, and epigenome analyses. The Programme encompasses computational approaches for variant discovery, gene expression profiling, network biology, and multi-omics data integration.

Principal Investigator: Prof. David Goukassian

University: Icahn School of Medicine at Mount Sinai

Research team: Recruitment in progress

Duration:2023-2027

Hosting partner: Institute of Molecular Biology NAS RA (IMB)

Project Importance The high likelihood of developing genomic instability due to exposure to ionizing radiation suggests that exposure can cause DNA damage to hematopoietic stem cells (HSCs), promoting the development of somatic mutations that can lead to aberrant clonal events. ...